Rivastigmine Exelon Patch 5
Find patient medical information for Rivastigmine Transdermal on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Exelon and Exelon patch (Rivastigmine) is a prescription drug for dementia. Side effects include weight loss, headache, stomach pain, and dizziness. Dosage, uses, and.
Slideshow Rivastigmine Patch Dosage and Administration Recommended Dosing Initial Dose Initiate treatment with one 4.6 mg/24 hours rivastigmine transdermal system applied to the skin once daily [see Dosage and Administration ()]. Dose Titration Increase the dose only after a minimum of 4 weeks at the previous dose, and only if the previous dose has been tolerated. For mild to moderate AD and PDD patients, continue the effective dose of 9.5 mg/24 hours for as long as therapeutic benefit persists. Patients can then be increased to the maximum effective dose of 13.3 mg/24 hours dose. For patients with severe AD, 13.3 mg/24 hours is the effective dose.
Doses higher than 13.3 mg/24 hours confer no appreciable additional benefit, and are associated with an increase in the incidence of adverse reactions [ see Warnings and Precautions (), Adverse Reactions ()]. Mild to Moderate Alzheimer’s Disease and Mild to Moderate Parkinson’s Disease Dementia The effective dosage of rivastigmine transdermal system is 9.5 mg/24 hours or 13.3 mg/24 hours administered once per day; replace with a new patch every 24 hours. Severe Alzheimer’s Disease The effective dosage of rivastigmine transdermal system in patients with severe Alzheimer’s disease is 13.3 mg/24 hours administered once per day; replace with a new patch every 24 hours. Smaart 7 Keygen Windows 2017 - Full Version 2017 more. Interruption of Treatment If dosing is interrupted for 3 days or fewer, restart treatment with the same or lower strength rivastigmine transdermal system. If dosing is interrupted for more than 3 days, restart treatment with the 4.6 mg/24 hours rivastigmine transdermal system and titrate as described above.
EXELON ® PATCH (rivastigmine transdermal system) is a prescription medicine used to treat mild, moderate, and severe memory problems (dementia. Daikin Brc1d5* Manual here. Exelon and Exelon patch (Rivastigmine) is a prescription drug for dementia. Side effects include weight loss, headache, stomach.
Dosing in Specific Populations Dosing Modifications in Patients with Hepatic Impairment Consider using the 4.6 mg/24 hours rivastigmine transdermal system as both the initial and maintenance dose in patients with mild (Child-Pugh score 5 to 6) to moderate (Child-Pugh score 7 to 9) hepatic impairment [see Use in Specific Populations ( ) and Clinical Pharmacology ()]. Dosing Modifications in Patients with Low Body Weight Carefully titrate and monitor patients with low body weight (. Table 4: Proportion of Adverse Reactions in the 24-week Double-Blind (DB) Treatment Phase (at Least 5% in Any Treatment Group) in Study 3 *Weight Decreased as presented in Table 4 is based upon clinical observations and/or adverse events reported by patients or caregivers. Body weight was monitored as a vital sign at prespecified time points throughout the course of the clinical study.
The proportion of patients who had weight loss equal to or greater than 7% of their baseline weight was 11% of those treated with rivastigmine transdermal system 4.6 mg/24 hours and 14. Siemens Wk6142 Instruction Manual more. 1% of those treated with rivastigmine transdermal system 13.3 mg/24 hours during the 24-week double-blind treatment. Preferred term Rivastigmine Transdermal System 13.3 mg/24 hours Rivastigmine Transdermal System 4.6 mg/24 hours Total number of patients studied 355 359 Total percentage of patients with ARs (%) 75 73 Application site erythema 13 12 Agitation 12 14 Urinary tract infection 8 10 Fall 8 6 Insomnia 7 4 Vomiting 7 3 Diarrhea 7 5 Weight decreased* 7 3 Nausea 6 3 Depression 5 4 Decreased appetite 5 1 Anxiety 5 5 Hallucination 2 5 Application Site Reactions Application site skin reactions leading to discontinuation were observed in ≤2.3% of rivastigmine transdermal system patients.
This number was 4.9% and 8.4% in the Chinese population and Japanese population, respectively. Cases of skin irritation were captured separately on an investigator-rated skin irritation scale.